3kn2: Difference between revisions
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{{STRUCTURE_3kn2| PDB=3kn2 | SCENE= }} | {{STRUCTURE_3kn2| PDB=3kn2 | SCENE= }} | ||
===HCV NS3 Protease Domain with ketoamide inhibitor=== | ===HCV NS3 Protease Domain with ketoamide inhibitor=== | ||
{{ABSTRACT_PUBMED_20004570}} | {{ABSTRACT_PUBMED_20004570}} | ||
==About this Structure== | ==About this Structure== | ||
[[3kn2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KN2 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020004570</ref><references group="xtra"/><references/> | ||
[[Category: Hepatitis c virus subtype 1a]] | [[Category: Hepatitis c virus subtype 1a]] | ||
[[Category: Bogen, S.]] | [[Category: Bogen, S.]] | ||
Line 47: | Line 31: | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
Revision as of 05:30, 4 April 2013
HCV NS3 Protease Domain with ketoamide inhibitorHCV NS3 Protease Domain with ketoamide inhibitor
Template:ABSTRACT PUBMED 20004570
About this StructureAbout this Structure
3kn2 is a 4 chain structure with sequence from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Nair LG, Sannigrahi M, Bogen S, Pinto P, Chen KX, Prongay A, Tong X, Cheng KC, Girijavallabhan V, George Njoroge F. P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile. Bioorg Med Chem Lett. 2010 Jan 15;20(2):567-70. Epub 2009 Nov 22. PMID:20004570 doi:10.1016/j.bmcl.2009.11.094
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Hepatitis c virus subtype 1a
- Bogen, S.
- Chen, K X.
- Nair, L G.
- Njoroge, G.
- Pinto, P.
- Prongay, A.
- Sannigrahi, M.
- Atp-binding
- Capsid protein
- Envelope protein
- Helicase
- Hepatitis c virus
- Host membrane
- Hydrolase
- Ketoamide inhibitor
- Membrane
- Ns3 protease domain
- Nucleotide-binding
- Rna replication
- Serine protease
- Transmembrane
- Virion