4hxr: Difference between revisions

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OCA

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-'''Unreleased structure'''
+{{STRUCTURE_4hxr|  PDB=4hxr  |  SCENE=  }}
+===Brd4 Bromodomain 1 complex with N-[3-(2-OXO-2,3-DIHYDRO-1,3-THIAZOL-4-YL)PHENYL]THIOPHENE-2-SULFONAMIDE inhibitor===
+{{ABSTRACT_PUBMED_23530754}}
-The entry 4hxr is ON HOLD  until Paper Publication
+==Disease==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
-Authors: Xiong, B., Cao, D.Y., Chen, W.Y., Chen, T.T., Xu, Y.C., Shen, J.K.
+==Function==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
-Description: Brd4 Bromodomain 1 complex with its novel inhibitors
+==About this Structure==
+[[4hxr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HXR OCA].
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Cao, D Y.]]
+[[Category: Chen, T T.]]
+[[Category: Chen, W Y.]]
+[[Category: Shen, J K.]]
+[[Category: Xiong, B.]]
+[[Category: Xu, Y C.]]
+[[Category: Brd4]]
+[[Category: Bromodomain]]
+[[Category: Four alpha helice]]
+[[Category: Protein binding-inhibitor complex]]