3zpr: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3zpr|  PDB=3zpr  |  SCENE=  }}
===Thermostabilised turkey beta1 adrenergic receptor with 4-methyl-2-(piperazin-1-yl) quinoline bound===
{{ABSTRACT_PUBMED_23517028}}


The entry 3zpr is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA]] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.


Authors: Christopher, J.A., Congreve, M., Dore, A.S., Marshall, F.H., Myszka, D.G., Brown, J., Koglin, M., Tehan, B., Errey, J.C., Tate, C.G., Warne, T.
==About this Structure==
 
[[3zpr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPR OCA].
Description: Thermostabilised turkey beta1 adrenergic receptor with 4-methyl-2-( piperazin-1-yl) quinoline bound
[[Category: Meleagris gallopavo]]
[[Category: Brown, J.]]
[[Category: Christopher, J A.]]
[[Category: Congreve, M.]]
[[Category: Dore, A S.]]
[[Category: Errey, J C.]]
[[Category: Koglin, M.]]
[[Category: Marshall, F H.]]
[[Category: Myszka, D G.]]
[[Category: Tate, C G.]]
[[Category: Tehan, B.]]
[[Category: Warne, T.]]
[[Category: Aryl piperazine]]
[[Category: Fragment screening]]
[[Category: Gpcr]]
[[Category: Membrane protein]]
[[Category: Structure based drug design]]

Revision as of 04:26, 4 April 2013

Template:STRUCTURE 3zpr

Thermostabilised turkey beta1 adrenergic receptor with 4-methyl-2-(piperazin-1-yl) quinoline boundThermostabilised turkey beta1 adrenergic receptor with 4-methyl-2-(piperazin-1-yl) quinoline bound

Template:ABSTRACT PUBMED 23517028

FunctionFunction

[ADRB1_MELGA] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.

About this StructureAbout this Structure

3zpr is a 2 chain structure with sequence from Meleagris gallopavo. Full crystallographic information is available from OCA.

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