Human growth hormone: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
Line 157: | Line 157: | ||
Certain medications can also be used in some combination with surgery and radiation. There are two classifications of acromegaly medication treatments. The first reduces HgH release from the pituitary. Somatostatin agonists reduce HgH release in approximately 50 percent of patients. They act by binding to somatostatin receptors, which regulate hormone control. The seemingly low level of success is due to certain tumors being resistant to somatostatin agonists. There are currently two somatostatin agonists on the market. Octreotide is a long acting release medication that needs to be injected about once a month. Lanreotide is a slow release medication that needs to be administered by injection about every other week. The second class of medication is an analog of HgH that competitively binds to HgH receptors, without activating them. Pegvisomant is an HgH analog that blocks the binding of HgH to HgH inhibitors. It is injected daily (Freda, 2002; A.D.A.M. Acromegaly). | Certain medications can also be used in some combination with surgery and radiation. There are two classifications of acromegaly medication treatments. The first reduces HgH release from the pituitary. Somatostatin agonists reduce HgH release in approximately 50 percent of patients. They act by binding to somatostatin receptors, which regulate hormone control. The seemingly low level of success is due to certain tumors being resistant to somatostatin agonists. There are currently two somatostatin agonists on the market. Octreotide is a long acting release medication that needs to be injected about once a month. Lanreotide is a slow release medication that needs to be administered by injection about every other week. The second class of medication is an analog of HgH that competitively binds to HgH receptors, without activating them. Pegvisomant is an HgH analog that blocks the binding of HgH to HgH inhibitors. It is injected daily (Freda, 2002; A.D.A.M. Acromegaly). | ||
==3D structures of human growth hormone== | |||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
[[1huw]], [[1hgu]] – HGH – human <br /> | |||
[[3hhr]], [[1hwg]], [[1kf9]] – HGH + HGH receptor<br /> | |||
[[1hwh]], [[1a22]] – HGH (mutant) + HGH receptor<br /> | |||
[[1axi]] – HGH (mutant) + HGH receptor (mutant)<br /> | |||
[[1bp3]] – HGH (mutant) + prolactin receptor<br /> |