3jrd: Difference between revisions
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{{STRUCTURE_3jrd| PDB=3jrd | SCENE= }} | {{STRUCTURE_3jrd| PDB=3jrd | SCENE= }} | ||
===Crystal structure of Fis bound to 27 bp DNA F25 containing T2A3 sequence at center=== | ===Crystal structure of Fis bound to 27 bp DNA F25 containing T2A3 sequence at center=== | ||
{{ABSTRACT_PUBMED_20395367}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI]] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref><ref>PMID:8836178</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3jrd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JRD OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020395367</ref><references group="xtra"/><references/> | ||
[[Category: Escherichia coli | [[Category: Escherichia coli]] | ||
[[Category: Cascio, D.]] | [[Category: Cascio, D.]] | ||
[[Category: Johnson, R C.]] | [[Category: Johnson, R C.]] | ||
| Line 38: | Line 25: | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulatio]] | [[Category: Transcription regulatio]] | ||
Revision as of 12:36, 27 March 2013
Crystal structure of Fis bound to 27 bp DNA F25 containing T2A3 sequence at centerCrystal structure of Fis bound to 27 bp DNA F25 containing T2A3 sequence at center
Template:ABSTRACT PUBMED 20395367
FunctionFunction
[FIS_ECOLI] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.[1][2]
About this StructureAbout this Structure
3jrd is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Ross W, Thompson JF, Newlands JT, Gourse RL. E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo. EMBO J. 1990 Nov;9(11):3733-42. PMID:2209559
- ↑ Wold S, Crooke E, Skarstad K. The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro. Nucleic Acids Res. 1996 Sep 15;24(18):3527-32. PMID:8836178