3hsm: Difference between revisions

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[[Image:3hsm.png|left|200px]]
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{{STRUCTURE_3hsm|  PDB=3hsm  |  SCENE=  }}  
{{STRUCTURE_3hsm|  PDB=3hsm  |  SCENE=  }}  
===Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1===
===Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1===
{{ABSTRACT_PUBMED_19541610}}


 
==Function==
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[[http://www.uniprot.org/uniprot/RYR1_RABIT RYR1_RABIT]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm. Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity).<ref>PMID:10388749</ref><ref>PMID:22036948</ref>  
The line below this paragraph, {{ABSTRACT_PUBMED_19541610}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_19541610}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:019541610</ref><references group="xtra"/>
<ref group="xtra">PMID:019541610</ref><references group="xtra"/><references/>
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Amador, F J.]]
[[Category: Amador, F J.]]
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[[Category: Wilson, A.]]
[[Category: Wilson, A.]]
[[Category: Beta-trefoil]]
[[Category: Beta-trefoil]]
[[Category: Calcium]]
[[Category: Calcium channel]]
[[Category: Calcium channel]]
[[Category: Calcium transport]]
[[Category: Calcium transport]]

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