3zfe: Difference between revisions

m Protected "3zfe" [edit=sysop:move=sysop]
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'''Unreleased structure'''
{{STRUCTURE_3zfe|  PDB=3zfe  |  SCENE=  }}
===Human enterovirus 71 in complex with capsid binding inhibitor WIN51711===


The entry 3zfe is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/A9X4C2_9ENTO A9X4C2_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611]  Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]


Authors: Plevka, P., Perera, R., Yap, M.L., Cardosa, J., Kuhn, R.J., Rossmann, M.G.
==About this Structure==
 
[[3zfe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_enterovirus_71 Human enterovirus 71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFE OCA].  
Description: Human enterovirus 71 in complex with capsid binding inhibitor WIN51711
[[Category: Human enterovirus 71]]
[[Category: Cardosa, J.]]
[[Category: Kuhn, R J.]]
[[Category: Perera, R.]]
[[Category: Plevka, P.]]
[[Category: Rossmann, M G.]]
[[Category: Yap, M L.]]
[[Category: Ev71]]
[[Category: Picornavirus]]
[[Category: Virus]]

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