1jyd: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_1jyd| PDB=1jyd | SCENE= }} | {{STRUCTURE_1jyd| PDB=1jyd | SCENE= }} | ||
===Crystal Structure of Recombinant Human Serum Retinol-Binding Protein at 1.7 A Resolution=== | |||
{{ABSTRACT_PUBMED_11604536}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:[http://omim.org/entry/180250 180250]]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. | |||
==About this Structure== | ==About this Structure== | ||
| Line 14: | Line 16: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:011604536</ref><references group="xtra"/> | <ref group="xtra">PMID:011604536</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Acharya, K R.]] | [[Category: Acharya, K R.]] | ||
Revision as of 10:23, 25 March 2013
Crystal Structure of Recombinant Human Serum Retinol-Binding Protein at 1.7 A ResolutionCrystal Structure of Recombinant Human Serum Retinol-Binding Protein at 1.7 A Resolution
Template:ABSTRACT PUBMED 11604536
DiseaseDisease
[RET4_HUMAN] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
FunctionFunction
[RET4_HUMAN] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
About this StructureAbout this Structure
1jyd is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.