1o7d: Difference between revisions
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{{STRUCTURE_1o7d| PDB=1o7d | SCENE= }} | {{STRUCTURE_1o7d| PDB=1o7d | SCENE= }} | ||
===THE STRUCTURE OF THE BOVINE LYSOSOMAL A-MANNOSIDASE SUGGESTS A NOVEL MECHANISM FOR LOW PH ACTIVATION=== | |||
{{ABSTRACT_PUBMED_12634058}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/MA2B1_BOVIN MA2B1_BOVIN]] Note=Defects in MAN2B1 are the cause of lysosomal alpha-mannosidosis (AM). AM is a lysosomal storage disease characterized by accumulation of unbranched oligosaccharide chains. The disease manifests itself by head tremor, aggressive tendency, ataxia, failure to thrive, and early death. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MA2B1_BOVIN MA2B1_BOVIN]] Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:012634058</ref><references group="xtra"/> | <ref group="xtra">PMID:012634058</ref><references group="xtra"/><references/> | ||
[[Category: Alpha-mannosidase]] | [[Category: Alpha-mannosidase]] | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] |