2wr6: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:2wr6.png|left|200px]]
 {{STRUCTURE_2wr6|  PDB=2wr6  |  SCENE=  }}
+===STRUCTURE OF THE COMPLEX OF RBP4 WITH LINOLEIC ACID===
-===STRUCTURE OF THE COMPLEX OF RBP4 WITH LINOLEIC ACID===
+==Disease==
+[[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:[http://omim.org/entry/180250 180250]]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
+==Function==
+[[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
 ==About this Structure==