3p8f: Difference between revisions

Revision as of 07:10, 25 March 2013

[SFTI1_HELAN] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.^[1]

3p8f is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Yuan C, Chen L, Meehan EJ, Daly N, Craik DJ, Huang M, Ngo JC. Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1. BMC Struct Biol. 2011 Jun 22;11:30. PMID:21693064 doi:10.1186/1472-6807-11-30

↑ Luckett S, Garcia RS, Barker JJ, Konarev AV, Shewry PR, Clarke AR, Brady RL. High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds. J Mol Biol. 1999 Jul 9;290(2):525-33. PMID:10390350 doi:10.1006/jmbi.1999.2891

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-[[Image:3p8f.jpg|left|200px]]
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 {{STRUCTURE_3p8f|  PDB=3p8f  |  SCENE=  }}
 ===Crystal Structure of MT-SP1 in complex with SFTI-1===
+{{ABSTRACT_PUBMED_21693064}}
+==Function==
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+[[http://www.uniprot.org/uniprot/SFTI1_HELAN SFTI1_HELAN]] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>
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 ==About this Structure==
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 ==Reference==
-<ref group="xtra">PMID:021693064</ref><references group="xtra"/>
+<ref group="xtra">PMID:021693064</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Matriptase]]