2f60: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

@@ Line 1: / Line 1: @@
-[[Image:2f60.png|left|200px]]
 {{STRUCTURE_2f60|  PDB=2f60  |  SCENE=  }}
+===Crystal Structure of the Dihydrolipoamide Dehydrogenase (E3)-Binding Domain of Human E3-Binding Protein===
+{{ABSTRACT_PUBMED_16442803}}
-===Crystal Structure of the Dihydrolipoamide Dehydrogenase (E3)-Binding Domain of Human E3-Binding Protein===
+==Disease==
+[[http://www.uniprot.org/uniprot/ODPX_HUMAN ODPX_HUMAN]] Defects in PDHX are the cause of pyruvate dehydrogenase E3-binding protein deficiency (PDHXD) [MIM:[http://omim.org/entry/245349 245349]].<ref>PMID:9399911</ref>
-{{ABSTRACT_PUBMED_16442803}}
+==Function==
+[[http://www.uniprot.org/uniprot/ODPX_HUMAN ODPX_HUMAN]] Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
 ==About this Structure==
@@ Line 14: / Line 16: @@
 ==Reference==
-<ref group="xtra">PMID:016442803</ref><references group="xtra"/>
+<ref group="xtra">PMID:016442803</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Brautigam, C A.]]