3l0k: Difference between revisions

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-{{Seed}}
-[[Image:3l0k.jpg|left|200px]]
-<!--
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 {{STRUCTURE_3l0k|  PDB=3l0k  |  SCENE=  }}
 ===Human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-UMP===
+{{ABSTRACT_PUBMED_19472232}}
+==Disease==
+[[http://www.uniprot.org/uniprot/PYR5_HUMAN PYR5_HUMAN]] Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:[http://omim.org/entry/258900 258900]]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.<ref>PMID:9042911</ref>
-<!--
+==About this Structure==
-The line below this paragraph, {{ABSTRACT_PUBMED_19472232}}, adds the Publication Abstract to the page
+[[3l0k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ex0 3ex0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0K OCA].
-(as it appears on PubMed at http://www.pubmed.gov), where 19472232 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_19472232}}
-==About this Structure==
+==See Also==
-L0K is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ex0 3ex0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0K OCA].
+*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
+*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]]
 ==Reference==
-<ref group="xtra">PMID:19472232</ref><references group="xtra"/>
+<ref group="xtra">PMID:019472232</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Orotidine-5'-phosphate decarboxylase]]
@@ Line 30: / Line 21: @@
 [[Category: Rudolph, M.]]
 [[Category: Decarboxylase]]
+[[Category: Lyase]]
 [[Category: Multifunctional enzyme]]
 [[Category: Pyrimidine biosynthesis]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:28:23 2010''