2gv7: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:2gv7.png|left|200px]]
 {{STRUCTURE_2gv7|  PDB=2gv7  |  SCENE=  }}
+===Structure of Matriptase in Complex with Inhibitor CJ-672===
+{{ABSTRACT_PUBMED_16821772}}
-===Structure of Matriptase in Complex with Inhibitor CJ-672===
+==Disease==
+[[http://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN]] Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH) [MIM:[http://omim.org/entry/610765 610765]]. ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.<ref>PMID:17273967</ref>
-{{ABSTRACT_PUBMED_16821772}}
+==Function==
+[[http://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN]] Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
 ==About this Structure==
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 ==Reference==
-<ref group="xtra">PMID:016821772</ref><references group="xtra"/>
+<ref group="xtra">PMID:016821772</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Bode, W.]]