2crk: Difference between revisions
New page: left|200px<br /><applet load="2crk" size="450" color="white" frame="true" align="right" spinBox="true" caption="2crk, resolution 2.35Å" /> '''MUSCLE CREATINE KINA... |
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[[Image:2crk.gif|left|200px]]<br /><applet load="2crk" size=" | [[Image:2crk.gif|left|200px]]<br /><applet load="2crk" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2crk, resolution 2.35Å" /> | caption="2crk, resolution 2.35Å" /> | ||
'''MUSCLE CREATINE KINASE'''<br /> | '''MUSCLE CREATINE KINASE'''<br /> | ||
==Overview== | ==Overview== | ||
The crystal structure of rabbit muscle creatine kinase, solved at 2.35 A | The crystal structure of rabbit muscle creatine kinase, solved at 2.35 A resolution by X-ray diffraction methods, clearly identified the active site with bound sulfates surrounded by a constellation of arginine residues. The putative binding site of creatine, which is occupied by a sulfate group in this analysis, has been tentatively identified. The dimeric interface of the enzyme is held together by a small number of hydrogen bonds. | ||
==About this Structure== | ==About this Structure== | ||
2CRK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2] Full crystallographic information is available from [http:// | 2CRK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CRK OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Bujacz, G.]] | [[Category: Bujacz, G.]] | ||
[[Category: Rao, J | [[Category: Rao, J K.]] | ||
[[Category: Wlodawer, A.]] | [[Category: Wlodawer, A.]] | ||
[[Category: SO4]] | [[Category: SO4]] | ||
[[Category: creatine kinase]] | [[Category: creatine kinase]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:51:54 2008'' | ||
