1d3k: Difference between revisions
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{{STRUCTURE_1d3k| PDB=1d3k | SCENE= }} | {{STRUCTURE_1d3k| PDB=1d3k | SCENE= }} | ||
===HUMAN SERUM TRANSFERRIN=== | |||
{{ABSTRACT_PUBMED_10739246}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/TRFE_HUMAN TRFE_HUMAN]] Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:[http://omim.org/entry/209300 209300]]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.<ref>PMID:11110675</ref><ref>PMID:15466165</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TRFE_HUMAN TRFE_HUMAN]] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:010739246</ref><references group="xtra"/> | <ref group="xtra">PMID:010739246</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Brayer, G D.]] | [[Category: Brayer, G D.]] | ||