1cjc: Difference between revisions
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{{STRUCTURE_1cjc| PDB=1cjc | SCENE= }} | {{STRUCTURE_1cjc| PDB=1cjc | SCENE= }} | ||
===STRUCTURE OF ADRENODOXIN REDUCTASE OF MITOCHONDRIAL P450 SYSTEMS=== | ===STRUCTURE OF ADRENODOXIN REDUCTASE OF MITOCHONDRIAL P450 SYSTEMS=== | ||
{{ABSTRACT_PUBMED_10369776}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ADRO_BOVIN ADRO_BOVIN]] Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. | |||
==About this Structure== | ==About this Structure== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:010369776</ref><ref group="xtra">PMID:017658942</ref><references group="xtra"/> | <ref group="xtra">PMID:010369776</ref><ref group="xtra">PMID:017658942</ref><references group="xtra"/><references/> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Schulz, G E.]] | [[Category: Schulz, G E.]] | ||
Revision as of 17:14, 21 March 2013
STRUCTURE OF ADRENODOXIN REDUCTASE OF MITOCHONDRIAL P450 SYSTEMSSTRUCTURE OF ADRENODOXIN REDUCTASE OF MITOCHONDRIAL P450 SYSTEMS
Template:ABSTRACT PUBMED 10369776
FunctionFunction
[ADRO_BOVIN] Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
About this StructureAbout this Structure
1cjc is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Ziegler GA, Vonrhein C, Hanukoglu I, Schulz GE. The structure of adrenodoxin reductase of mitochondrial P450 systems: electron transfer for steroid biosynthesis. J Mol Biol. 1999 Jun 18;289(4):981-90. PMID:10369776 doi:10.1006/jmbi.1999.2807
- ↑ Ojha S, Meng EC, Babbitt PC. Evolution of function in the "two dinucleotide binding domains" flavoproteins. PLoS Comput Biol. 2007 Jul;3(7):e121. PMID:17658942 doi:10.1371/journal.pcbi.0030121