3ii5: Difference between revisions

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[[Image:3ii5.png|left|200px]]
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{{STRUCTURE_3ii5|  PDB=3ii5  |  SCENE=  }}  
{{STRUCTURE_3ii5|  PDB=3ii5  |  SCENE=  }}  
===The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor===
===The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor===
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{{ABSTRACT_PUBMED_19864136}}
{{ABSTRACT_PUBMED_19864136}}


==About this Structure==
==About this Structure==
3II5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II5 OCA].  
[[3ii5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II5 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19864136</ref><references group="xtra"/>
<ref group="xtra">PMID:019864136</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
Line 32: Line 16:
[[Category: Torres, N.]]
[[Category: Torres, N.]]
[[Category: Xu, W.]]
[[Category: Xu, W.]]
[[Category: Acetylation]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: B-raf]]
[[Category: B-raf]]
[[Category: Cardiomyopathy]]
[[Category: Cardiomyopathy]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Kinase]]
[[Category: Kinase]]
Line 43: Line 25:
[[Category: Phorbol-ester binding]]
[[Category: Phorbol-ester binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
[[Category: Proto-oncogene]]
[[Category: Proto-oncogene]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 17:20:31 2009''

Revision as of 14:01, 13 March 2013

Template:STRUCTURE 3ii5

The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitorThe Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor

Template:ABSTRACT PUBMED 19864136

About this StructureAbout this Structure

3ii5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Berger DM, Torres N, Dutia M, Powell D, Ciszewski G, Gopalsamy A, Levin JI, Kim KH, Xu W, Wilhelm J, Hu Y, Collins K, Feldberg L, Kim S, Frommer E, Wojciechowicz D, Mallon R. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. Epub 2009 Oct 26. PMID:19864136 doi:10.1016/j.bmcl.2009.10.049

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OCA
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