2btf: Difference between revisions
New page: left|200px<br /><applet load="2btf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2btf, resolution 2.55Å" /> '''THE STRUCTURE OF CRY... |
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[[Image:2btf.gif|left|200px]]<br /><applet load="2btf" size=" | [[Image:2btf.gif|left|200px]]<br /><applet load="2btf" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2btf, resolution 2.55Å" /> | caption="2btf, resolution 2.55Å" /> | ||
'''THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN'''<br /> | '''THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN'''<br /> | ||
==Overview== | ==Overview== | ||
The three-dimensional structure of bovine profilin-beta-actin has been | The three-dimensional structure of bovine profilin-beta-actin has been solved to 2.55 A resolution by X-ray crystallography. There are several significant local changes in the structure of beta-actin compared with alpha-actin as well as an overall 5 degrees rotation between its two major domains. Actin molecules in the crystal are organized into ribbons through intermolecular contacts like those found in oligomeric protein assemblies. Profilin forms two extensive contacts with the actin ribbon, one of which appears to correspond to the solution contact in vitro. | ||
==About this Structure== | ==About this Structure== | ||
2BTF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with SR, ACE, CH3 and ATP as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | 2BTF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=SR:'>SR</scene>, <scene name='pdbligand=ACE:'>ACE</scene>, <scene name='pdbligand=CH3:'>CH3</scene> and <scene name='pdbligand=ATP:'>ATP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BTF OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Goonesekere, N | [[Category: Goonesekere, N C.W.]] | ||
[[Category: Myslik, J | [[Category: Myslik, J C.]] | ||
[[Category: Rozycki, M | [[Category: Rozycki, M D.]] | ||
[[Category: Schutt, C | [[Category: Schutt, C E.]] | ||
[[Category: ACE]] | [[Category: ACE]] | ||
[[Category: ATP]] | [[Category: ATP]] | ||
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[[Category: acetylation and actin-binding]] | [[Category: acetylation and actin-binding]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:41:26 2008'' | ||
Revision as of 17:41, 21 February 2008
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THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN
OverviewOverview
The three-dimensional structure of bovine profilin-beta-actin has been solved to 2.55 A resolution by X-ray crystallography. There are several significant local changes in the structure of beta-actin compared with alpha-actin as well as an overall 5 degrees rotation between its two major domains. Actin molecules in the crystal are organized into ribbons through intermolecular contacts like those found in oligomeric protein assemblies. Profilin forms two extensive contacts with the actin ribbon, one of which appears to correspond to the solution contact in vitro.
About this StructureAbout this Structure
2BTF is a Protein complex structure of sequences from Bos taurus with , , and as ligands. Full crystallographic information is available from OCA.
ReferenceReference
The structure of crystalline profilin-beta-actin., Schutt CE, Myslik JC, Rozycki MD, Goonesekere NC, Lindberg U, Nature. 1993 Oct 28;365(6449):810-6. PMID:8413665
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