Troponin: Difference between revisions

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[[Troponin]] (Tn) is a regulatory protein in muscle contraction.  It contains 3 subunits: TnC causes conformational change in TnI when it binds to calcium ions.  TnT binds to [[Tropomyosin|tropomyosin]] and TnI binds to actin which is found in thin muscle filaments. The images at the left and at the right correspond to one representative Tn, ''i.e.'' the crystal structure of complex Troponin C/Troponin I/Troponin T ([[1yv0]]).  See additional details in[[Human Cardiac Troponin C]].
[[Troponin]] (Tn) is a regulatory protein in muscle contraction.  It contains 3 subunits: TnC causes conformational change in TnI when it binds to calcium ions.  For more details on TnC see [[ Role of Troponin C in decreased muscle sensitivity to calcium]].  TnT binds to [[Tropomyosin|tropomyosin]] and TnI binds to actin which is found in thin muscle filaments. The images at the left and at the right correspond to one representative Tn, ''i.e.'' the crystal structure of complex Troponin C/Troponin I/Troponin T ([[1yv0]]).  See additional details in[[Human Cardiac Troponin C]].


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== 3D Structures of Troponin ==
== 3D Structures of Troponin ==


''Update February 2013''
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}


=== Troponin C+Troponin I+Troponin T ===
=== Troponin C+Troponin I+Troponin T ===

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Alexander Berchansky, Michal Harel, Joel L. Sussman