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{{STRUCTURE_2vel| PDB=2vel | SCENE= }} | {{STRUCTURE_2vel| PDB=2vel | SCENE= }} | ||
===STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES=== | ===STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES=== | ||
{{ABSTRACT_PUBMED_18239072}} | {{ABSTRACT_PUBMED_18239072}} | ||
Revision as of 14:05, 11 March 2013
STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIESSTRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES
Template:ABSTRACT PUBMED 18239072
About this StructureAbout this Structure
2vel is a 2 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Alahuhta M, Salin M, Casteleijn MG, Kemmer C, El-Sayed I, Augustyns K, Neubauer P, Wierenga RK. Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties. Protein Eng Des Sel. 2008 Apr;21(4):257-66. Epub 2008 Jan 31. PMID:18239072 doi:http://dx.doi.org/10.1093/protein/gzn002
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Triose-phosphate isomerase
- Trypanosoma brucei brucei
- Alahuhta, M.
- Augustyns, K.
- Casteleijn, M G.
- El-Sayed, I.
- Kemmer, C.
- Neubauer, P.
- Salin, M.
- Wierenga, R K.
- Binding pocket
- Engineering
- Enzyme
- Fatty acid biosynthesis
- Gluconeogenesis
- Glycolysis
- Glycosome
- Isomerase
- Lipid synthesis
- Monomeric
- Pentose shunt
- Substrate specificity
- Tim
- Tim barrel
- Triosephosphate isomerase