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{{STRUCTURE_3pp0| PDB=3pp0 | SCENE= }} | {{STRUCTURE_3pp0| PDB=3pp0 | SCENE= }} | ||
===Crystal Structure of the Kinase domain of Human HER2 (erbB2).=== | ===Crystal Structure of the Kinase domain of Human HER2 (erbB2).=== | ||
{{ABSTRACT_PUBMED_21454582}} | {{ABSTRACT_PUBMED_21454582}} | ||
==About this Structure== | ==About this Structure== | ||
[[3pp0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP0 OCA]. | [[3pp0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP0 OCA]. | ||
==See Also== | |||
*[[Journal:JBSD:35|Journal:JBSD:35]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021454582</ref><references group="xtra"/> | <ref group="xtra">PMID:021454582</ref><ref group="xtra">doi 10.1080/07391102.2012.736773</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] |
Revision as of 12:19, 11 March 2013
Crystal Structure of the Kinase domain of Human HER2 (erbB2).Crystal Structure of the Kinase domain of Human HER2 (erbB2).
Template:ABSTRACT PUBMED 21454582
About this StructureAbout this Structure
3pp0 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Aertgeerts K, Skene R, Yano J, Sang BC, Zou H, Snell G, Jennings A, Iwamoto K, Habuka N, Hirokawa A, Ishikawa T, Tanaka T, Miki H, Ohta Y, Sogabe S. Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein. J Biol Chem. 2011 May 27;286(21):18756-65. Epub 2011 Mar 30. PMID:21454582 doi:10.1074/jbc.M110.206193
- ↑ Tsou YA, Chen KC, Chang SS, Wen YR, Chen CY. A possible strategy against head and neck cancer: in silico investigation of three-in-one inhibitors. J Biomol Struct Dyn. 2012 Nov 12. PMID:23140436 doi:10.1080/07391102.2012.736773
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Homo sapiens
- Receptor protein-tyrosine kinase
- Aertgeerts, K.
- Skene, R J.
- Sogabe, S.
- Anti-oncogene
- Atp-binding
- Cell cycle
- Disease mutation
- Glycoprotein
- Kinase domain
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Receptor
- Secreted
- Transferase
- Transferase-transferase inhibitor complex
- Transmembrane
- Tyrosine kinase inhibitor
- Tyrosine-protein kinase