2b6g: Difference between revisions

Revision as of 17:34, 21 February 2008

RNA recognition by the Vts1 SAM domain

OverviewOverview

The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop.

About this StructureAbout this Structure

2B6G is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

ReferenceReference

RNA recognition by the Vts1p SAM domain., Johnson PE, Donaldson LW, Nat Struct Mol Biol. 2006 Feb;13(2):177-8. Epub 2006 Jan 22. PMID:16429155

Page seeded by OCA on Thu Feb 21 16:34:39 2008

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OCA

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-[[Image:2b6g.gif|left|200px]]<br /><applet load="2b6g" size="450" color="white" frame="true" align="right" spinBox="true"
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 caption="2b6g" />
 '''RNA recognition by the Vts1 SAM domain'''<br />
 ==Overview==
-The putative yeast post-transcriptional regulator Vts1p and its related, protein Smaug, from Drosophila melanogaster, each use a sterile alpha, motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition, element (SRE). Here, we present the NMR structures of the Vts1p-SRE, complex and the free SRE. Structural highlights include the direct, recognition of a guanine base and the formation or stabilization of a base, pair in the SRE loop.
+The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop.
 ==About this Structure==
-B6G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2B6G OCA].
+B6G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6G OCA].
 ==Reference==
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 [[Category: Saccharomyces cerevisiae]]
 [[Category: Single protein]]
-[[Category: Donaldson, L.W.]]
+[[Category: Donaldson, L W.]]
-[[Category: Johnson, P.E.]]
+[[Category: Johnson, P E.]]
 [[Category: alpha-helix]]
 [[Category: hairpin]]
 [[Category: pentaloop]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 08:36:02 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:34:39 2008''