Actin: Difference between revisions
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[[Image:3hbt.png|left|200px|thumb|Crystal Structure of Native G-actin [[3hbt]]]] | [[Image:3hbt.png|left|200px|thumb|Crystal Structure of Native G-actin [[3hbt]]]] | ||
{{STRUCTURE_3hbt| PDB=3hbt | SIZE=400| SCENE=Actin/Cv/1 |right|CAPTION=Native G-actin with methyl-histidine complex with ATP, sulfate and Ca+2 ion [[3hbt]] }} | {{STRUCTURE_3hbt| PDB=3hbt | SIZE=400| SCENE=Actin/Cv/1 |right|CAPTION=Native G-actin with methyl-histidine complex with ATP, sulfate and Ca+2 ion [[3hbt]] }} | ||
[[Actin]] is a protein found in all eukaryotic cells. It is the monomer of two types of filaments: microfilaments which are part of the cytoskeleton and thin filaments which are part of muscles. Three isoforms of actin are identified: α (Aa) (or G-actin) found in muscle tissue, β (Ab) and γ (Ag) actins are components of the cytoskeleton. F-actin is Aa bound to ATP. The images at the left and at the right correspond to one representative Actin, ''i.e.'' the crystal structure of rabbit Native G-actin ([[3hbt]]). For more details see [[F-actin]] and [[Non-polymerizable monomeric actin]]. <scene name='Actin/Cv/2'>Click here to see the difference between 2 conformations of bovine Ag actin</scene> (PDB entries [[1hlu]] and [[2btf]]; morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]). | [[Actin]] is a protein found in all eukaryotic cells. It is the monomer of two types of filaments: microfilaments which are part of the cytoskeleton and thin filaments which are part of muscles. Three isoforms of actin are identified: α (Aa) (or G-actin) found in muscle tissue, β (Ab) and γ (Ag) actins are components of the cytoskeleton. F-actin is Aa bound to ATP. The images at the left and at the right correspond to one representative Actin, ''i.e.'' the crystal structure of rabbit Native G-actin ([[3hbt]]). For more details see [[F-actin]] and [[Non-polymerizable monomeric actin]]. <scene name='Actin/Cv/2'>Click here to see the difference between 2 conformations of bovine Ag actin</scene> (PDB entries [[1hlu]] and [[2btf]]; morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]). | ||
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== 3D Structures of Actin == | == 3D Structures of Actin == | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
=== α actin 1 (Aa) === | === α actin 1 (Aa) === | ||