CD44: Difference between revisions
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< | <Structure load='2jcq' size='400' frame='true' align='right' caption='Structure of mouse CD44 hyaluronan-binding domain complex with 8-mer HA (PDB entry [[2jcq]])' scene='Insert optional scene name here' /> | ||
'''CD44''' is a glycoprotein involved in cell-cell interactions. CD44 is a receptor of hyaluronic acid (HA). CD44 undergoes post-translational modification. Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow. | '''CD44''' is a glycoprotein involved in cell-cell interactions. CD44 is a receptor of hyaluronic acid (HA). CD44 undergoes post-translational modification. Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow. | ||
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[[2jcp]] - mCD44 hyaluronan-binding domain – mouse<br /> | [[2jcp]] - mCD44 hyaluronan-binding domain – mouse<br /> | ||
[[2jcq]], [[2jcr]] - mCD44 hyaluronan-binding domain + 8-mer HA | [[2jcq]], [[2jcr]] - mCD44 hyaluronan-binding domain + 8-mer HA | ||
[[Category:Topic Page]] | |||
Revision as of 17:43, 6 March 2013
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CD44 is a glycoprotein involved in cell-cell interactions. CD44 is a receptor of hyaluronic acid (HA). CD44 undergoes post-translational modification. Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.
3D structures of CD443D structures of CD44
1uuh – hCD44 hyaluronan-binding domain – human
1poz, 2i83 - hCD44 hyaluronan-binding domain – NMR
2jcp - mCD44 hyaluronan-binding domain – mouse
2jcq, 2jcr - mCD44 hyaluronan-binding domain + 8-mer HA