3e88: Difference between revisions

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[[Image:3e88.png|left|200px]]
[[Image:3e88.png|left|200px]]


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{{STRUCTURE_3e88|  PDB=3e88  |  SCENE=  }}  
{{STRUCTURE_3e88|  PDB=3e88  |  SCENE=  }}  


===Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors===
===Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors===


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{{ABSTRACT_PUBMED_19179070}}
{{ABSTRACT_PUBMED_19179070}}


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==Reference==
==Reference==
<ref group="xtra">PMID:19179070</ref><references group="xtra"/>
<ref group="xtra">PMID:019179070</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Smallwood, A.]]
[[Category: Smallwood, A.]]
[[Category: Ward, P.]]
[[Category: Ward, P.]]
[[Category: Akt2]]
[[Category: Atp-binding]]
[[Category: Gsk3 beta]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Wnt signaling pathway]]

Revision as of 18:38, 27 February 2013

File:3e88.png

Template:STRUCTURE 3e88

Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitorsCrystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors

Template:ABSTRACT PUBMED 19179070

About this StructureAbout this Structure

3e88 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Rouse MB, Seefeld MA, Leber JD, McNulty KC, Sun L, Miller WH, Zhang S, Minthorn EA, Concha NO, Choudhry AE, Schaber MD, Heerding DA. Aminofurazans as potent inhibitors of AKT kinase. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1508-11. Epub 2009 Jan 9. PMID:19179070 doi:10.1016/j.bmcl.2009.01.002

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OCA