3h63: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:3h63.png|left|200px]] | |||
[[Image:3h63. | |||
{{STRUCTURE_3h63| PDB=3h63 | SCENE= }} | {{STRUCTURE_3h63| PDB=3h63 | SCENE= }} | ||
===Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)=== | ===Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)=== | ||
{{ABSTRACT_PUBMED_19601647}} | {{ABSTRACT_PUBMED_19601647}} | ||
==About this Structure== | ==About this Structure== | ||
[[3h63]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H63 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019601647</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phosphoprotein phosphatase]] | [[Category: Phosphoprotein phosphatase]] | ||
| Line 31: | Line 19: | ||
[[Category: Luchinat, C.]] | [[Category: Luchinat, C.]] | ||
[[Category: Talluri, E.]] | [[Category: Talluri, E.]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| Line 43: | Line 30: | ||
[[Category: Protein phosphatase]] | [[Category: Protein phosphatase]] | ||
[[Category: Tpr repeat]] | [[Category: Tpr repeat]] | ||
Revision as of 18:22, 27 February 2013
Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)
Template:ABSTRACT PUBMED 19601647
About this StructureAbout this Structure
3h63 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Bertini I, Calderone V, Fragai M, Luchinat C, Talluri E. Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin. J Med Chem. 2009 Aug 13;52(15):4838-43. PMID:19601647 doi:10.1021/jm900610k