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New page: left|200px<br /> <applet load="2aex" size="450" color="white" frame="true" align="right" spinBox="true" caption="2aex, resolution 1.58Å" /> '''The 1.58A Crystal S... |
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[[Image:2aex.gif|left|200px]]<br /> | [[Image:2aex.gif|left|200px]]<br /><applet load="2aex" size="350" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="2aex" size=" | |||
caption="2aex, resolution 1.58Å" /> | caption="2aex, resolution 1.58Å" /> | ||
'''The 1.58A Crystal Structure of Human Coproporphyrinogen Oxidase Reveals the Structural Basis of Hereditary Coproporphyria'''<br /> | '''The 1.58A Crystal Structure of Human Coproporphyrinogen Oxidase Reveals the Structural Basis of Hereditary Coproporphyria'''<br /> | ||
==Disease== | ==Disease== | ||
Known diseases associated with this structure: Chondrodysplasia punctata, X-linked dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300205 300205]], Cleft palate with ankyloglossia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300307 300307 | Known diseases associated with this structure: Chondrodysplasia punctata, X-linked dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300205 300205]], Cleft palate with ankyloglossia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300307 300307]], Coproporphyria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=121300 121300]], Harderoporphyrinuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=121300 121300]] | ||
==About this Structure== | ==About this Structure== | ||
2AEX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with CIT as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coproporphyrinogen_oxidase Coproporphyrinogen oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.3 1.3.3.3] Full crystallographic information is available from [http:// | 2AEX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coproporphyrinogen_oxidase Coproporphyrinogen oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.3 1.3.3.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEX OCA]. | ||
[[Category: Coproporphyrinogen oxidase]] | [[Category: Coproporphyrinogen oxidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Demeler, B.]] | [[Category: Demeler, B.]] | ||
[[Category: Flachsova, E.]] | [[Category: Flachsova, E.]] | ||
[[Category: Lee, D | [[Category: Lee, D S.]] | ||
[[Category: Martasek, P.]] | [[Category: Martasek, P.]] | ||
[[Category: Raman, C | [[Category: Raman, C S.]] | ||
[[Category: CIT]] | [[Category: CIT]] | ||
[[Category: flat beta-sheet sandwiched by helices]] | [[Category: flat beta-sheet sandwiched by helices]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:26:41 2008'' | ||
Revision as of 17:26, 21 February 2008
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The 1.58A Crystal Structure of Human Coproporphyrinogen Oxidase Reveals the Structural Basis of Hereditary Coproporphyria
DiseaseDisease
Known diseases associated with this structure: Chondrodysplasia punctata, X-linked dominant OMIM:[300205], Cleft palate with ankyloglossia OMIM:[300307], Coproporphyria OMIM:[121300], Harderoporphyrinuria OMIM:[121300]
About this StructureAbout this Structure
2AEX is a Single protein structure of sequence from Homo sapiens with as ligand. Active as Coproporphyrinogen oxidase, with EC number 1.3.3.3 Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 16:26:41 2008