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[[Actin]] is a protein found in all eukaryotic cells.  It is the monomer of two types of filaments: microfilaments which are part of the cytoskeleton and thin filaments which are part of muscles.  Three isoforms of actin are identified: α (Aa) (or G-actin) found in muscle tissue, β (Ab) and γ (Ag) actins  are components of the cytoskeleton.  F-actin is Aa bound to ATP. The images at the left and at the right correspond to one representative Actin, ''i.e.'' the crystal structure of rabbit Native G-actin ([[3hbt]]).  For more details see [[F-actin]] and [[Non-polymerizable monomeric actin]]. <scene name='Actin/Cv/2'>Click here to see the difference between 2 conformations of bovine Ag actin</scene> (PDB entries [[1hlu]] and [[2btf]]; morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]).  
[[Actin]] is a protein found in all eukaryotic cells.  It is the monomer of two types of filaments: microfilaments which are part of the cytoskeleton and thin filaments which are part of muscles.  Three isoforms of actin are identified: α (Aa) (or G-actin) found in muscle tissue, β (Ab) and γ (Ag) actins  are components of the cytoskeleton.  F-actin is Aa bound to ATP. The images at the left and at the right correspond to one representative Actin, ''i.e.'' the crystal structure of rabbit Native G-actin ([[3hbt]]).  For more details see [[F-actin]] and [[Non-polymerizable monomeric actin]]. <scene name='Actin/Cv/2'>Click here to see the difference between 2 conformations of bovine Ag actin</scene> (PDB entries [[1hlu]] and [[2btf]]; morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]).  


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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman