Insulin-Degrading Enzyme: Difference between revisions
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<StructureSection load="3tuv" size="400" color="" frame="true" spin="on" Scene= align="right" caption='Rat insulin-degrading enzyme complex with peptide (green) and ATP, [[3tuv]]' > | <StructureSection load="3tuv" size="400" color="" frame="true" spin="on" Scene= align="right" caption='Rat insulin-degrading enzyme complex with peptide (green) and ATP, [[3tuv]]' > | ||
[[Image:2g49.png|left|200px]] | [[Image:2g49.png|left|200px]] | ||
[[Insulin-Degrading Enzyme]] (PDB entry [[2g49]]) is a highly conserved 2*113 kDa homodimeric zinc metalloprotease. It belongs to the M16A family of metalloproteases within the ME clan. It hydrolyses insulin and several amyloidogenic peptides like amyloid-β (Aβ). | [[Insulin-Degrading Enzyme]] (PDB entry [[2g49]]) is a highly conserved 2*113 kDa homodimeric zinc metalloprotease. It belongs to the M16A family of metalloproteases within the ME clan. It hydrolyses insulin and several amyloidogenic peptides like amyloid-β (Aβ). | ||