Fasciculin: Difference between revisions
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{{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin [[1fas]] }} | {{STRUCTURE_1fas| PDB=1fas | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin [[1fas]] }} | ||
[[Fasciculin|Fasciculins]] ( | [[Fasciculin|Fasciculins]] (FAS) are toxins produced by the snake green mamba. FAS1 and FAS2 are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, ''i.e.'' the crystal structure of Fasciculin 1 ([[1fas]]). For toxins in Proteopedia see [[Toxins]]. | ||
Revision as of 13:18, 4 February 2013
Fasciculins (FAS) are toxins produced by the snake green mamba. FAS1 and FAS2 are known to bind to acetylcholinesterase (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, i.e. the crystal structure of Fasciculin 1 (1fas). For toxins in Proteopedia see Toxins.
3D Structures of Fasciculin3D Structures of Fasciculin
Update January 2013
FasciculinFasciculin
FAS+ AChEFAS+ AChE
2x8b, 1b41, 4ey8 – FAS2+hAChE – human
1f8u - FAS2+hAChE (mutant)
1ku6, 1mah - FAS2+mAChE – mouse
1fss - FAS2+AChE – Torpedo californica