2hg8: Difference between revisions

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m Protected "2hg8" [edit=sysop:move=sysop]
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[[Image:2hg8.png|left|200px]]
[[Image:2hg8.png|left|200px]]


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{{STRUCTURE_2hg8|  PDB=2hg8  |  SCENE=  }}  
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===Crystal Structure of Cys315Ala mutant of human mitochondrial branched chain aminotransferase complexed with its substrate mimic, N-methyl leucine.===
===Crystal Structure of Cys315Ala mutant of human mitochondrial branched chain aminotransferase complexed with its substrate mimic, N-methyl leucine.===


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{{ABSTRACT_PUBMED_17050531}}


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==Reference==
==Reference==
<ref group="xtra">PMID:17050531</ref><ref group="xtra">PMID:9478945</ref><ref group="xtra">PMID:9165094</ref><references group="xtra"/>
<ref group="xtra">PMID:017050531</ref><ref group="xtra">PMID:009478945</ref><references group="xtra"/>
[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Yennawar, N H.]]
[[Category: Yennawar, N H.]]
[[Category: D-aminoacid aminotransferase-like plp-dependent enzyme]]
[[Category: D-aminoacid aminotransferase-like plp-dependent enzyme]]
[[Category: Transferase]]

Revision as of 15:34, 23 January 2013

File:2hg8.png

Template:STRUCTURE 2hg8

Crystal Structure of Cys315Ala mutant of human mitochondrial branched chain aminotransferase complexed with its substrate mimic, N-methyl leucine.Crystal Structure of Cys315Ala mutant of human mitochondrial branched chain aminotransferase complexed with its substrate mimic, N-methyl leucine.

Template:ABSTRACT PUBMED 17050531

About this StructureAbout this Structure

2hg8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. Yennawar NH, Islam MM, Conway M, Wallin R, Hutson SM. Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis. J Biol Chem. 2006 Dec 22;281(51):39660-71. Epub 2006 Oct 18. PMID:17050531 doi:10.1074/jbc.M607552200
  2. Davoodi J, Drown PM, Bledsoe RK, Wallin R, Reinhart GD, Hutson SM. Overexpression and characterization of the human mitochondrial and cytosolic branched-chain aminotransferases. J Biol Chem. 1998 Feb 27;273(9):4982-9. PMID:9478945

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OCA