2gni: Difference between revisions

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m Protected "2gni" [edit=sysop:move=sysop]
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[[Image:2gni.png|left|200px]]
[[Image:2gni.png|left|200px]]


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{{STRUCTURE_2gni|  PDB=2gni  |  SCENE=  }}  
{{STRUCTURE_2gni|  PDB=2gni  |  SCENE=  }}  


===PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)===
===PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)===


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{{ABSTRACT_PUBMED_16699172}}
{{ABSTRACT_PUBMED_16699172}}


==About this Structure==
==About this Structure==
[[2gni]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNI OCA].  
[[2gni]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNI OCA].  
==See Also==
*[[CAMP-dependent protein kinase|CAMP-dependent protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16699172</ref><ref group="xtra">PMID:14656443</ref><references group="xtra"/>
<ref group="xtra">PMID:016699172</ref><ref group="xtra">PMID:014656443</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: CAMP-dependent protein kinase]]
[[Category: CAMP-dependent protein kinase]]
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[[Category: Rho-kinase]]
[[Category: Rho-kinase]]
[[Category: Surrogate]]
[[Category: Surrogate]]
[[Category: Transferase/transferase inhibitor complex]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 15:22, 23 January 2013

File:2gni.png

Template:STRUCTURE 2gni

PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)

Template:ABSTRACT PUBMED 16699172

About this StructureAbout this Structure

2gni is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D. Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity. J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:16699172 doi:10.1074/jbc.M512374200
  2. ↑ Breitenlechner C, Gassel M, Hidaka H, Kinzel V, Huber R, Engh RA, Bossemeyer D. Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure. 2003 Dec;11(12):1595-607. PMID:14656443

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