Group:MUZIC:Tritopodin: Difference between revisions

Revision as of 12:39, 11 January 2013 view source Irela Gretchen Reza Mazar (talk \| contribs) 218 edits No edit summary ← Older edit		Revision as of 13:12, 11 January 2013 view source Irela Gretchen Reza Mazar (talk \| contribs) 218 edits No edit summary Newer edit →
Line 5:		Line 5:

	==Sequence Annotation==		==Sequence Annotation==
	Tritopodin share 33% of homology in the Aminoacid sequence with Myopodin and 30% with Synaptopodin <ref> PMID:9314539 </ref>, which makes believe similar functions for both proteins. Tritopodin gene it is form by 5 exons and 3 isoforms ~~are~~ postulated: mCHAPa from exon 1,2,3 and 5, as well as mCHAPb that result from a start-codon in exon 4, from which derives two proteins variants of 140kDa (mCHAPa) and 110kDa (mCHAPb) <ref> PMID:20215401 </ref> and .		Tritopodin share 33% of homology in the Aminoacid sequence with Myopodin and 30% with Synaptopodin <ref> PMID:9314539 </ref>, which makes believe similar functions for both proteins. Tritopodin gene it is form by 5 exons and 2 isoforms were predicted in human 79kDa and 102.5kDa and in mouse 79kDa and 103kDa. After running SDS gel Beqqali et al. postulated mCHAPa from exon 1,2,3 and 5, as well as mCHAPb that result from a start-codon in exon 4, from which derives two proteins variants of 140kDa (mCHAPa) and 110kDa (mCHAPb) <ref> PMID:20215401 </ref> and .