3cem: Difference between revisions

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{{Seed}}
[[Image:3cem.png|left|200px]]
[[Image:3cem.png|left|200px]]


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{{STRUCTURE_3cem|  PDB=3cem  |  SCENE=  }}  
{{STRUCTURE_3cem|  PDB=3cem  |  SCENE=  }}  


===Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE9423===
===Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE9423===


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{{ABSTRACT_PUBMED_18373353}}
{{ABSTRACT_PUBMED_18373353}}
==Disease==
Known disease associated with this structure: Glycogen storage disease VI OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=232700 232700]]


==About this Structure==
==About this Structure==
3CEM is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEM OCA].  
[[3cem]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEM OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18373353</ref><references group="xtra"/>
<ref group="xtra">PMID:018373353</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphorylase]]
[[Category: Phosphorylase]]
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[[Category: Schmoll, D.]]
[[Category: Schmoll, D.]]
[[Category: Wendt, K U.]]
[[Category: Wendt, K U.]]
[[Category: Acetylation]]
[[Category: Allosteric enzyme]]
[[Category: Allosteric enzyme]]
[[Category: Allosteric inhibitor]]
[[Category: Allosteric inhibitor]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein ligand complex]]
[[Category: Protein ligand complex]]
[[Category: Pyridoxal phosphate]]
[[Category: Pyridoxal phosphate]]
[[Category: Tense state]]
[[Category: Tense state]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:39:50 2009''

Revision as of 23:57, 7 January 2013

File:3cem.png

Template:STRUCTURE 3cem

Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE9423Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE9423

Template:ABSTRACT PUBMED 18373353

About this StructureAbout this Structure

3cem is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Anderka O, Loenze P, Klabunde T, Dreyer MK, Defossa E, Wendt KU, Schmoll D. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91. Epub 2008 Mar 29. PMID:18373353 doi:10.1021/bi702397d

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