3bwm: Difference between revisions

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{{Seed}}
[[Image:3bwm.png|left|200px]]
[[Image:3bwm.png|left|200px]]


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===Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC===
===Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC===


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{{ABSTRACT_PUBMED_18486144}}
{{ABSTRACT_PUBMED_18486144}}
==Disease==
Known disease associated with this structure: Panic disorder, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=116790 116790]], Schizophrenia, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=116790 116790]]


==About this Structure==
==About this Structure==
3BWM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWM OCA].  
[[3bwm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWM OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18486144</ref><references group="xtra"/>
<ref group="xtra">PMID:018486144</ref><references group="xtra"/>
[[Category: Catechol O-methyltransferase]]
[[Category: Catechol O-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Catecholamine metabolism]]
[[Category: Catecholamine metabolism]]
[[Category: Comt]]
[[Category: Comt]]
[[Category: Cytoplasm]]
[[Category: Dnc]]
[[Category: Dnc]]
[[Category: Magnesium]]
[[Category: Magnesium]]
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[[Category: Methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Neurotransmitter degradation]]
[[Category: Neurotransmitter degradation]]
[[Category: Polymorphism]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
[[Category: S-adenosyl-l-methionine]]
[[Category: S-adenosyl-l-methionine]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:10:43 2009''

Revision as of 23:46, 7 January 2013

File:3bwm.png

Template:STRUCTURE 3bwm

Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNCCrystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC

Template:ABSTRACT PUBMED 18486144

About this StructureAbout this Structure

3bwm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Rutherford K, Le Trong I, Stenkamp RE, Parson WW. Crystal structures of human 108V and 108M catechol O-methyltransferase. J Mol Biol. 2008 Jun 27;380(1):120-30. Epub 2008 Apr 23. PMID:18486144 doi:10.1016/j.jmb.2008.04.040

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