1xl5: Difference between revisions
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New page: left|200px<br /> <applet load="1xl5" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xl5, resolution 1.73Å" /> '''HIV-1 Protease in c... |
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[[Image:1xl5.gif|left|200px]]<br /> | [[Image:1xl5.gif|left|200px]]<br /><applet load="1xl5" size="350" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="1xl5" size=" | |||
caption="1xl5, resolution 1.73Å" /> | caption="1xl5, resolution 1.73Å" /> | ||
'''HIV-1 Protease in complex with amidhyroxysulfone'''<br /> | '''HIV-1 Protease in complex with amidhyroxysulfone'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
1XL5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with CL and 190 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http:// | 1XL5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=190:'>190</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XL5 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: hiv protease]] | [[Category: hiv protease]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:55:59 2008'' | ||
Revision as of 16:56, 21 February 2008
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HIV-1 Protease in complex with amidhyroxysulfone
About this StructureAbout this Structure
1XL5 is a Single protein structure of sequence from Human immunodeficiency virus 1 with and as ligands. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.
ReferenceReference
An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors., Specker E, Bottcher J, Lilie H, Heine A, Schoop A, Muller G, Griebenow N, Klebe G, Angew Chem Int Ed Engl. 2005 May 13;44(20):3140-4. PMID:15822136
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