2ka6: Difference between revisions

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[[Image:2ka6.png|left|200px]]
[[Image:2ka6.png|left|200px]]


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{{STRUCTURE_2ka6|  PDB=2ka6  |  SCENE=  }}  
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===NMR structure of the CBP-TAZ2/STAT1-TAD complex===
===NMR structure of the CBP-TAZ2/STAT1-TAD complex===


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{{ABSTRACT_PUBMED_19214187}}
{{ABSTRACT_PUBMED_19214187}}
==Disease==
Known disease associated with this structure: Mycobacterial infection, atypical, familial disseminated OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600555 600555]], STAT1 deficiency, complete OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600555 600555]]


==About this Structure==
==About this Structure==
2KA6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. The February 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Enhanceosome''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_2 10.2210/rcsb_pdb/mom_2010_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KA6 OCA].  
[[2ka6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. The February 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Enhanceosome''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_2 10.2210/rcsb_pdb/mom_2010_2]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KA6 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19214187</ref><references group="xtra"/>
<ref group="xtra">PMID:019214187</ref><references group="xtra"/>
[[Category: Enhanceosome]]
[[Category: Enhanceosome]]
[[Category: Histone acetyltransferase]]
[[Category: Histone acetyltransferase]]
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[[Category: Wojciak, J M.]]
[[Category: Wojciak, J M.]]
[[Category: Wright, P E.]]
[[Category: Wright, P E.]]
[[Category: Acetylation]]
[[Category: Activator]]
[[Category: Activator]]
[[Category: Alternative splicing]]
[[Category: Antiviral defense]]
[[Category: Antiviral defense]]
[[Category: Bromodomain]]
[[Category: Bromodomain]]
[[Category: Cbp/p300]]
[[Category: Cbp/p300]]
[[Category: Chromosomal rearrangement]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Dna-binding]]
[[Category: Dna-binding]]
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[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Sh2 domain]]
[[Category: Sh2 domain]]
[[Category: Stat1]]
[[Category: Stat1]]
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[[Category: Transcription regulator]]
[[Category: Transcription regulator]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Ubl conjugation]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 22:19:27 2010''

Revision as of 18:00, 7 January 2013

File:2ka6.png

Template:STRUCTURE 2ka6

NMR structure of the CBP-TAZ2/STAT1-TAD complexNMR structure of the CBP-TAZ2/STAT1-TAD complex

Template:ABSTRACT PUBMED 19214187

About this StructureAbout this Structure

2ka6 is a 2 chain structure with sequence from Homo sapiens and Mus musculus. The February 2010 RCSB PDB Molecule of the Month feature on Enhanceosome by David Goodsell is 10.2210/rcsb_pdb/mom_2010_2. Full experimental information is available from OCA.

ReferenceReference

[xtra 1]

  1. Wojciak JM, Martinez-Yamout MA, Dyson HJ, Wright PE. Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains. EMBO J. 2009 Apr 8;28(7):948-58. Epub 2009 Feb 12. PMID:19214187 doi:10.1038/emboj.2009.30

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