1w39: Difference between revisions

Revision as of 16:40, 21 February 2008

CRYSTAL STRUCTURE OF AN ARTIFICIAL TOP COMPONENT OF TURNIP YELLOW MOSAIC VIRUS

OverviewOverview

Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection.

About this StructureAbout this Structure

1W39 is a Single protein structure of sequence from Turnip yellow mosaic virus. Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of an empty capsid of turnip yellow mosaic virus., van Roon AM, Bink HH, Plaisier JR, Pleij CW, Abrahams JP, Pannu NS, J Mol Biol. 2004 Aug 27;341(5):1205-14. PMID:15321716

Page seeded by OCA on Thu Feb 21 15:40:00 2008

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OCA

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-[[Image:1w39.gif|left|200px]]<br /><applet load="1w39" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1w39.gif|left|200px]]<br /><applet load="1w39" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1w39, resolution 3.75&Aring;" />
 '''CRYSTAL STRUCTURE OF AN ARTIFICIAL TOP COMPONENT OF TURNIP YELLOW MOSAIC VIRUS'''<br />
 ==Overview==
-Empty capsids (artificial top component) of turnip yellow mosaic virus, were co-crystallized with an encapsidation initiator RNA hairpin. No clear, density was observed for the RNA, but there were clear differences in the, conformation of a loop of the coat protein at the opening of the, pentameric capsomer (formed by five A-subunits) protruding from the, capsid, compared to the corresponding loop in the intact virus. Further, differences were found at the N terminus of the A-subunit. These, differences have implications for the mechanism of decapsidation of the, virus, required for infection.
+Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection.
 ==About this Structure==
-W39 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W39 OCA].
+W39 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W39 OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Single protein]]
 [[Category: Turnip yellow mosaic virus]]
-[[Category: Abrahams, J.P.]]
+[[Category: Abrahams, J P.]]
-[[Category: Bink, H.H.J.]]
+[[Category: Bink, H H.J.]]
-[[Category: Pannu, N.S.]]
+[[Category: Pannu, N S.]]
-[[Category: Plaisier, J.R.]]
+[[Category: Plaisier, J R.]]
-[[Category: Pleij, C.W.A.]]
+[[Category: Pleij, C W.A.]]
-[[Category: Roon, A.M.M.Van.]]
+[[Category: Roon, A M.M Van.]]
 [[Category: artificial top component]]
 [[Category: capsid protein]]
@@ Line 27: / Line 27: @@
 [[Category: virus/viral protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 05:12:58 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:40:00 2008''