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HPBP is the only known transporter capable of binding phosphate ions in human plasma.
HPBP is the only known transporter capable of binding phosphate ions in human plasma.
It may become a new predictor of or a potential therapeutic agent for phosphate-related diseases such as atherosclerosis, since we know that a high phosphate amount is linked to cardio-vascular diseases, by inducing atheromatous plaques (lipid sediments) in arteries.
It may become a new predictor of or a potential therapeutic agent for phosphate-related diseases such as atherosclerosis, since it is known that a high phosphate amount is linked to cardio-vascular diseases, by inducing atheromatous plaques (lipid sediments) in arteries.


On the other hand, scientists were able to demonstrate a connexion between HPBP and HIV-1 gene transcription. The data proved that HPBP blocks HIV1-LTR (Long Terminal Repeats) promoted expression and replication, preventing HIV1 virus to multiply. It also works on mutant HIV strains. This discovery opens up a new drug research field, which could be explored in order to find an innovative HIV-treatment.<ref>PMID:21762475</ref>
On the other hand, scientists were able to demonstrate a connexion between HPBP and HIV-1 gene transcription. The data proved that HPBP is most likely able to block HIV1-LTR (Long Terminal Repeats) promoted expression and replication, preventing the HIV1 virus to multiply. It also works on mutant HIV strains. This discovery opens up a completely new field for drug research, which could lead to an innovative HIV-treatment.<ref>PMID:21762475</ref>


== '''External Resources''' ==
== '''External Resources''' ==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA, Christine Ponkratz