Sandbox Reserved 703: Difference between revisions
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HPBP is the only known transporter capable of binding phosphate ions in human plasma. | HPBP is the only known transporter capable of binding phosphate ions in human plasma. | ||
It may become a new predictor of or a potential therapeutic agent for phosphate-related diseases such as atherosclerosis, since | It may become a new predictor of or a potential therapeutic agent for phosphate-related diseases such as atherosclerosis, since it is known that a high phosphate amount is linked to cardio-vascular diseases, by inducing atheromatous plaques (lipid sediments) in arteries. | ||
On the other hand, scientists were able to demonstrate a connexion between HPBP and HIV-1 gene transcription. The data proved that HPBP | On the other hand, scientists were able to demonstrate a connexion between HPBP and HIV-1 gene transcription. The data proved that HPBP is most likely able to block HIV1-LTR (Long Terminal Repeats) promoted expression and replication, preventing the HIV1 virus to multiply. It also works on mutant HIV strains. This discovery opens up a completely new field for drug research, which could lead to an innovative HIV-treatment.<ref>PMID:21762475</ref> | ||
== '''External Resources''' == | == '''External Resources''' == |