1uzc: Difference between revisions
New page: left|200px<br /><applet load="1uzc" size="450" color="white" frame="true" align="right" spinBox="true" caption="1uzc" /> '''THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYP... |
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'''THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11'''<br /> | '''THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11'''<br /> | ||
==Overview== | ==Overview== | ||
The FF domain is a 60 amino acid residue phosphopeptide-binding module | The FF domain is a 60 amino acid residue phosphopeptide-binding module found in a variety of eukaryotic proteins including the transcription elongation factor CA150, the splicing factor Prp40 and p190RHOGAP. We have determined the structure of an FF domain from HYPA/FBP11. The domain is composed of three alpha helices arranged in an orthogonal bundle with a 3(10) helix in the loop between the second and third alpha helices. The structure differs from those of other phosphopeptide-binding domains and represents a novel phosphopeptide-binding fold. | ||
==About this Structure== | ==About this Structure== | ||
1UZC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure | 1UZC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1H40. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZC OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Allen, M | [[Category: Allen, M D.]] | ||
[[Category: Bycroft, M.]] | [[Category: Bycroft, M.]] | ||
[[Category: Friedler, A.]] | [[Category: Friedler, A.]] | ||
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[[Category: transcription]] | [[Category: transcription]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:29:59 2008'' | ||
Revision as of 16:30, 21 February 2008
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THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11
OverviewOverview
The FF domain is a 60 amino acid residue phosphopeptide-binding module found in a variety of eukaryotic proteins including the transcription elongation factor CA150, the splicing factor Prp40 and p190RHOGAP. We have determined the structure of an FF domain from HYPA/FBP11. The domain is composed of three alpha helices arranged in an orthogonal bundle with a 3(10) helix in the loop between the second and third alpha helices. The structure differs from those of other phosphopeptide-binding domains and represents a novel phosphopeptide-binding fold.
About this StructureAbout this Structure
1UZC is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1H40. Full crystallographic information is available from OCA.
ReferenceReference
The structure of an FF domain from human HYPA/FBP11., Allen M, Friedler A, Schon O, Bycroft M, J Mol Biol. 2002 Oct 25;323(3):411-6. PMID:12381297
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