Sandbox Reserved 703: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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 == '''Applications''' ==
-HPBP is the only known transporter capable of binding phosphate ions in human plasma [1].
+HPBP is the only known transporter capable of binding phosphate ions in human plasma.
-It may become a new predictor of or a potential therapeutic agent for phosphate-related diseases such as atherosclerosis [1], since we know that a high phosphate amount is linked to cardio-vascular diseases, by inducing atheromatous plaques (lipid sediments) in arteries.
+It may become a new predictor of or a potential therapeutic agent for phosphate-related diseases such as atherosclerosis, since we know that a high phosphate amount is linked to cardio-vascular diseases, by inducing atheromatous plaques (lipid sediments) in arteries.
 On the other hand, scientists were able to demonstrate a connexion between HPBP and HIV-1 gene transcription. The data proved that HPBP blocks HIV1-LTR (Long Terminal Repeats) promoted expression and replication, preventing HIV1 virus to multiply. It also works on mutant HIV strains. This discovery opens up a new drug research field, which could be explored in order to find an innovative HIV-treatment.<ref>PMID:21762475</ref>