1x7y: Difference between revisions

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[[Image:1x7y.png|left|200px]]
[[Image:1x7y.png|left|200px]]


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===Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase===
===Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase===


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{{ABSTRACT_PUBMED_15576032}}
{{ABSTRACT_PUBMED_15576032}}
==Disease==
Known disease associated with this structure: Maple syrup urine disease, type Ia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608348 608348]], Maple syrup urine disease, type Ib OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=248611 248611]]


==About this Structure==
==About this Structure==
1X7Y is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X7Y OCA].  
[[1x7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X7Y OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15576032</ref><references group="xtra"/>
<ref group="xtra">PMID:015576032</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chuang, D T.]]
[[Category: Chuang, D T.]]
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[[Category: Branched-chain]]
[[Category: Branched-chain]]
[[Category: Flavoprotein]]
[[Category: Flavoprotein]]
[[Category: Ketoacid dehydrogenase]]
[[Category: Multi-enzyme complex]]
[[Category: Multi-enzyme complex]]
[[Category: Oxidative decarboxylation maple syrup urine disease]]
[[Category: Oxidative decarboxylation maple syrup urine disease]]
[[Category: Oxidoreductase,ketoacid dehydrogenase]]
[[Category: Oxidoreductase]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Thiamin diphosphate]]
[[Category: Thiamin diphosphate]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:54:15 2009''

Revision as of 14:50, 5 January 2013

File:1x7y.png

Template:STRUCTURE 1x7y

Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenaseCrystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase

Template:ABSTRACT PUBMED 15576032

About this StructureAbout this Structure

1x7y is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Wynn RM, Kato M, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation. Structure. 2004 Dec;12(12):2185-96. PMID:15576032 doi:10.1016/j.str.2004.09.013

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