1pv8: Difference between revisions

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{{Seed}}
[[Image:1pv8.png|left|200px]]
[[Image:1pv8.png|left|200px]]


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===Crystal structure of a low activity F12L mutant of human porphobilinogen synthase===
===Crystal structure of a low activity F12L mutant of human porphobilinogen synthase===


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{{ABSTRACT_PUBMED_12897770}}
{{ABSTRACT_PUBMED_12897770}}
==Disease==
Known disease associated with this structure: Porphyria, acute hepatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=125270 125270]], Lead poisoning, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=125270 125270]]


==About this Structure==
==About this Structure==
1PV8 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PV8 OCA].  
[[1pv8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PV8 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:12897770</ref><references group="xtra"/>
<ref group="xtra">PMID:012897770</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Porphobilinogen synthase]]
[[Category: Porphobilinogen synthase]]
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[[Category: Reaction intermediate]]
[[Category: Reaction intermediate]]
[[Category: Tetrapyrrole biosynthesis]]
[[Category: Tetrapyrrole biosynthesis]]
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