Caspase-3 Regulatory Mechanisms: Difference between revisions

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== Caspase-3 Regulation==
== Caspase-3 Regulation==


<StructureSection load='1dq8' size='350' side='right' caption='Structure of Caspase-3 with substrate bound (PDB entry [[2H5I]])' scene='Caspase-3_Regulatory_Mechanisms/Scene1/1'>
<StructureSection load='1I3O' size='350' side='right' caption='Structure of Caspase-3 with BIR2 domain (PDB entry [[1I3O]])' scene='Caspase-3_Regulatory_Mechanisms/Bir2/1'>


=== Exosite and Allosteric Site===
=== Exosite and Allosteric Site===
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==== Natural Inhibitors====
==== Natural Inhibitors====
X-linked inhibitor of apoptosis proteins (XIAP) contains the second baculovirus IAP repeat domain (BIR2) targeting caspase-3 and caspase-7.
X-linked inhibitor of apoptosis proteins (XIAP) contains the second baculovirus IAP repeat domain (BIR2) targeting caspase-3 and caspase-7. <scene name='Caspase-3_Regulatory_Mechanisms/Bir2/1'>BIR2</scene>


=Reference=
=Reference=

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Scott Eron, Banyuhay P. Serrano, Yunlong Zhao, Jaime Prilusky, Michal Harel, Alexander Berchansky