CBI Molecules: Difference between revisions

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Knapp lab
Knapp lab
   
   
:'''[[Molecular Playground/Prolyl Hydroxylase Domain (PHD) Enzyme]]''', Cristina Martin
:'''[[Molecular Playground/Prolyl Hydroxylase Domain (PHD) Enzyme]]''', Cristina Martin, Serap Pektas
:: Best CBI Molecule Proteopedia Page 2010
:: Best CBI Molecule Proteopedia Page 2010



Revision as of 23:50, 12 December 2012

These are molecules under study by members of the University of Massachusetts Amherst Chemistry-Biology Interface Program. Many of the molecules we study are featured at the Molecular Playground (see also Molecular Playground in Proteopedia). Follow the links below to read nontechnical descriptions, in Proteopedia, of these molecules.

UMass CBI Members, add your molecules to the list (which is alphabetical by CBI research mentor); follow the instructions below the list.

Fall 2012: CBI Molecules are due 12/12/12 and should be added at the TOP of the list from your lab. Label it as "in progress" until you are finished. For those editing an existing CBI Molecule, start from that entry so that it retains the full author list of all authors that contributed (or include credits to the original page and authors if it does not -- I may be able to request additions to the author list).


MoleculesMolecules

** Designates CBI Molecules Featured on CBI website

Bhatia Lab

Molecular Playground/Alginate-Fall2011, Joe White, David Griffin
Molecular Playground/Alginate-Fall2010, Joe White, David Griffin
Molecular Playground/Poly(ethylene glycol), Erika M. Saffer


Chambers Lab

Molecular Playground/Glutamate Receptor, Amanda Hussey, Steve McCarron, Rosie Combs-Bachmann, Mariel Feliciano


Chien Lab

**Molecular Playground/Hexameric ClpX, Joanne Lau
Best CBI Molecule 2011
Molecular Playground/DNA replication initiator DnaA, Jing Liu


Forbes Lab

Molecular Playground/CheR, Miaomin Zhang
Molecular Playground/RBP, Jan Panteli
Molecular Playground/TRAIL, Charley Swofford


Garman Lab

Molecular Playground/Human Protective Protein Cathepsin A, Yadilette Rivera-Colon
Molecular Playground/Human PPCA, Nilima Kolli


Gierasch Lab

Molecular Playground/CRABP I, Kristine Faye Pobre, Mylene Ferrolino,Mangai Periasamy
Best Overall CBI Molecule 2010
Molecular Playground/CRABP I (Cellular Retinoic Acid Binding Protein), Gustavo Elberto Epalza Sanchez

(compare this to the previous version above to see what's new)

**Molecular_Playground/DHFR, Karan Hingorani
Best CBI Molecule 2012


Hardy Lab

Molecular Playground/Caspase-6 and neurodegeneration, Kevin Buadlart Dagbay
Molecular Playground/Caspase-7 Dynamics
Molecular Playground/Caspase-9 Regulation, Kristen Huber
Molecular Playground/Caspase-6 (new), Elih Velazquez
Molecular Playground/Influenza A M2 transmembrane domain, Samantha Nicholls
Molecular Playground/Dengue Virus Protease, Muslum Yildiz


Hebert Lab

Molecular Playground/Saposin C, Abla Tannous
Molecular_Playground/ERMan1, Johan Sunryd


Heuck Lab

Molecular_Playground/Pcr H, Fabian Romano


Kaltashov Lab

Molecular Playground/Transferrin, Khaja Muneeruddin
Molecular Playground/Velaglucerase, Adriana Kita


Knapp lab

Molecular Playground/Prolyl Hydroxylase Domain (PHD) Enzyme, Cristina Martin, Serap Pektas
Best CBI Molecule Proteopedia Page 2010
Molecular Playground/FIH, Cornelius Taabazuing, Breanne Holmes, John Hangasky


Maroney Lab

Molecular Playground/Nickel Superoxide Dismutase, Carolyn Carr
Molecular Playground/CsoR and RcnR, Heidi Hu


Martin Lab

**Molecular Playground/T7 RNAP Conformations, Luis E. Ramirez-Tapia
Best CBI Molecule 2011
Molecular Playground/T7 RNA Polymerase (7 mer int), Ankit Vahia
Molecular Playground/Human mtRNA pol, Ketan Mathavan


Peyton Lab

Molecular Playground/C-Raf, Thuy Nguyen
Molecular Playground/FAK, Dannielle Ryman


Roberts Lab

Molecular Playground/Taxol, Rohan Patil, Sarah Wilson
Molecular Playground/Insulin, Whitney Stoppel


Rotello Lab

Molecular Playground/Reverse Transcriptase, Daniel Moyano-Marino
Molecular Playground/Pancreatic Lipase, Rui Tang
Molecular playground/Chymotrypsin, Brad
Molecular Playground/Targeting Peptide, David Solfiell


Schnarr Lab

Molecular Playground/Sfp, Jon Amoroso, Gitanjeli Prasad, Lawrence Sheringham Borketey
Molecular Playground/6-Deoxyerythronolide B Synthase, Tsung-Yi Lin, Jon Amoroso
Molecular Playground/ACP apo, Gitanjeli Prasad


Tew Lab

Molecular Playground/HIV Tat, Brittany deRonde


Thayumanavan Lab

Molecular Playground/Lysozyme , Daniella Gonzalez
Molecular Playground/Beta-galactosidase, Judy Ventura
Molecular Playground/Carbonic Anhydrase, Krishna Reddy Raghupathi
Molecular Playground/Avidin, Rami Rajasekar Reddy
Molecular Playground/Biotin binding avidin, Diego Amado
Molecular Playground/MMP12, Jiaming Zhuang
Molecular Playground/Gluconase, Jing Guo
Molecular Playground/Glutathione Reductase, Reuben Chacko


Thayumanavan & Vachet Labs

Molecular Playground/Trypsin, Gladys Murage


Thompson & Weis Labs

Molecular Playground/Bacterial Chemotaxis Receptors, Lynmarie K. Thompson, Shiela M. Jones
Molecular Playground/cytoplasmic domain of a serine chemotaxis receptor, Meili Yang
Molecular Playground/Cytoplasmic domain of chemoreceptor of Thermotoga maritima, Xuni Li


Vachet Lab

Molecular playground/beta 2 microglobulin, Nick Borotto
Best CBI Molecule Jmol scenes 2010
Molecular Playground/Myoglobin, Yuping Zhou
Molecular Playground/ Copper-Zinc Superoxide Dismutase, Shaynah Browne


Other Molecules of interest

Molecular Playground/PcrA Helicase, Luis E Ramirez-Tapia, Martin Lab


Other Laboratories

Molecular Playground/YKL-40, Ralph A. Francescone III, Shao Lab
Molecular Playground/β-lactoglobulin, Daniel Seeman, Dubin Lab
Molecular Playground/ADAM13, Genevieve Abbruzzese, Alfandari Lab

InstructionsInstructions

Congratulations to the prize-winning CBI molecules noted above! The new goal is for students to work collaboratively to create one excellent CBI Molecule for each CBI research group, to be featured on the CBI website.

Fall 2012: Complete steps 1-3 by 10/10/12, in preparation for the CBI Molecule Workshop.

1. If you don't already have one, request a Proteopedia account and log in.

2. Get started working in Proteopedia by using the links at Help:Contents. Make yourself a sandbox page: Enter "User:Your Name/Sandbox 1" (omit quotes) in the search box, then follow instructions to edit this page. Practice entering text, inserting a structure window with scrolling text (green 4-square button on the right), and creating a green scene. You can look at other Proteopedia pages in edit mode to see how different effects (like colored text) are achieved (but this won't show you how the scene effects are made).

3. Get together with the other Chalk Talk students in your research group and decide which molecule you will improve or create. Develop ideas for the scenes you wish to show. You will work on these during the workshop with our help, and then finish them on your own.

You are encouraged to collaborate on this year's CBI Molecules, but everyone will need to do some editing of the molecule so that they each appear as authors on the final list. If you are the sole student from your group enrolled in Chalk Talk and have not previously made a CBI Molecule, try to convince another group member who has previously made a CBI Molecule (see list above) to join us for the workshop so that you can work together.

A successful CBI Molecule will be an interesting, nontechnical description of a molecule related to your group's research. It should not be super long, but instead have multiple green scenes. Green scenes should clearly show an interesting feature and should be attractive. Use the green scenes to help you make interesting points about the molecule (do not try to describe every feature of the molecule). It's great if you can end with a brief statement about how it relates to your group's research goals.

4. Your final pages should be called "Molecular Playground/your molecule" and should have links on this CBI Molecule page -- put the new ones first on the list from your research group. Label them "in progress" until you are finished.

Links to HELP pagesLinks to HELP pages

Overview at Help:Contents

See also Help:Getting_Started_in_Proteopedia

Videos showing how to use Proteopedia: Proteopedia:Video_Guide (Sometimes slow -- if you pause the video and wait awhile it will download and then you can play it without interruptions)

Proteopedia Scenes: Do It Yourself gives succinct step by step instructions on how to create a molecular scene.

A powerpoint-like set of slides that walks a user through the process of creating a new page and a new molecular scene/green link. Proteopedia Workshop Slides

Proteopedia:Guidelines for Ethical Writing. Please pay attention to the section about images. There are links to examples of images re-used with explicit permission.

For other help resources, click on Help in the navigation box at the upper left of every page in Proteopedia.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Lynmarie K Thompson, Tsung-Yi Lin, Daniella C. Gonzalez-Toro, Judy Ventura, Daniel Moyano-Marino, Charles Swofford, Rohan Patil, Yadilette Rivera-Colon, Ralph A. Francescone III, Krishna Reddy Ragupathi, Rami Rajasekhar Reddy, Johan Sunryd, Whitney Stoppel, Ankit Vahia, Nilima Kolli, David Griffin, Mariel Feliciano, Diego Amado-Torres, John Hangasky, Jiaming Zhuang, Rui Tang, Gladys Wanjiku Murage, Nick Borotto, Jing Guo, Bradley Duncan, Kristine Faye Pobre, Cristina B. Martin, Mangai Periasamy, Reuben Chacko, Adriana Kita, Daniel Seeman, Kristen Huber, Samantha B. Nicholls, David Solfiell, Luis E Ramirez-Tapia, Shiela M. Jones, Yuping Zhou, Sarah Wilson, Gitanjeli Prasad, Genevieve Abbruzzese, Meili Yang, Joanne Lau, Muslum Yildiz, Joe White, Shaynah Browne, Miaomin Zhang, Erika M. Saffer, Jan Panteli, Abla Tannous, Eric Martz, Jaime Prilusky, Ketan Mathavan, Karan Hingorani, Khaja Muneeruddin, Xuni Li, Thuy V. Nguyen, Brittany deRonde, Dannielle Ryman, Heidi Hu, Kevin Buadlart Dagbay, Gustavo Elberto Epalza Sanchez, Jing Liu, Carolyn Carr, Serap Pektas, Carrie Morrison Penland, Lawrence Sheringham Borketey, Lydia Lamriben, Jake Pawlowski, Banyuhay P. Serrano, Elizabeth R. Haglin, Jing Huang, Christina Chisholm, Mine Canakci, Zhe Zhang, Carolina Morell-Perez, Lauren Jansen, Katrina Rieger, Kamal K. Joshi, Derek MacPherson, Vanessa Chaplin, Bib Yang, Chengfeng Ren, Huan He, Mahalia Serrano, Maryam Kashefy, Yunlong Zhao, Joseph Tilitsky, Priyanka Basak, Hsin-Ting Huang, Joseph Hardie, Yuzhou Tang, Robert Vass, Elizabeth Cummings, Tyler Marcinko, Coralie Backlund, Jill Graham, Keith Ballard, Ololade Fatunmbi, Mallory Gordon