CD44: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
Michal Harel (talk | contribs)
31,761 edits
No edit summary
Michal Harel (talk | contribs)
31,761 edits
No edit summary
Line 5: Line 5:
'''CD44''' is a glycoprotein involved in cell-cell interactions.  CD44 is a receptor of hyaluronic acid (HA).  CD44 undergoes post-translational modification.  Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.
'''CD44''' is a glycoprotein involved in cell-cell interactions.  CD44 is a receptor of hyaluronic acid (HA).  CD44 undergoes post-translational modification.  Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.


==3D structures of CD44==


[[1uuh]] – hCD44 hyaluronan-binding domain – human<br />
[[1uuh]] – hCD44 hyaluronan-binding domain – human<br />

Revision as of 16:05, 12 December 2012



Structure of mouse CD44 hyaluronan-binding domain complex with 8-mer HA (PDB entry 2jcq)

Drag the structure with the mouse to rotate

CD44 is a glycoprotein involved in cell-cell interactions. CD44 is a receptor of hyaluronic acid (HA). CD44 undergoes post-translational modification. Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.

3D structures of CD443D structures of CD44

1uuh – hCD44 hyaluronan-binding domain – human
1poz, 2i83 - hCD44 hyaluronan-binding domain – NMR
2jcp - mCD44 hyaluronan-binding domain – mouse
2jcq, 2jcr - mCD44 hyaluronan-binding domain + 8-mer HA

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=CD44&oldid=1631103"