Antibody: Difference between revisions

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[[Image:Opening 1igt.png|450px|left|thumb| Intact Immunoglobulin, [[1igt]]]]
[[Image:Opening 1igt.png|450px|left|thumb| Intact Immunoglobulin, [[1igt]]]]
{{STRUCTURE_1hzh| right| PDB=1hzh  | SCENE=Antibody/1hzh_starting_scene/3 |CAPTION= Crystal Structure of the Intact Human IGG B12: A Template for a Potential HIV Vaccine, [[1hzh]] }}
{{STRUCTURE_1hzh| right| PDB=1hzh  | SCENE=Antibody/1hzh_starting_scene/3 |CAPTION= Crystal Structure of the Intact Human IGG B12: A Template for a Potential HIV Vaccine, [[1hzh]] }}
'''Antibodies''', also known as Immunoglobulins (Ig) are gamma globulin proteins, primarily found in the blood of vertebrates.  These [[glycoproteins]] serve as a critical component of the immune system when the host fails to activate alternative compliment pathways or phagocytic cells in response to invading microorganisms or other [http://en.wikipedia.org/wiki/Antigen antigens]. The incredible specificity with which immunoglobulins bind to an antigen is based upon structural complementarity between the antigen and antibody <scene name='Antibody/1hzh_heavy_chains/1'>heavy </scene>and <scene name='Antibody/1hzh_light_chains/1'>light chains </scene>. It is this specificity that has made <scene name='Antibody/1hzh_starting_scene/3'>antibodies</scene> a critical component in laboratory and medical research.  See more in [[Monoclonal Antibody]].  For Anti-HIV Fab see [[Human Fab PG16]].
'''Antibodies''', also known as '''Immunoglobulins''' (Ig) are gamma globulin proteins, primarily found in the blood of vertebrates.  These [[glycoproteins]] serve as a critical component of the immune system when the host fails to activate alternative compliment pathways or phagocytic cells in response to invading microorganisms or other [http://en.wikipedia.org/wiki/Antigen antigens]. The incredible specificity with which immunoglobulins bind to an antigen is based upon structural complementarity between the antigen and antibody <scene name='Antibody/1hzh_heavy_chains/1'>heavy </scene>and <scene name='Antibody/1hzh_light_chains/1'>light chains </scene>. It is this specificity that has made <scene name='Antibody/1hzh_starting_scene/3'>antibodies</scene> a critical component in laboratory and medical research.  See more in [[Monoclonal Antibody]].  For Anti-HIV Fab see [[Human Fab PG16]].


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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Eric Martz, David Canner, Wayne Decatur, Alexander Berchansky, Michal Harel, Mark Hoelzer