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1o5d: Difference between revisions

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{{Seed}}
[[Image:1o5d.png|left|200px]]
[[Image:1o5d.png|left|200px]]


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{{STRUCTURE_1o5d|  PDB=1o5d  |  SCENE=  }}  
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===Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)===
===Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)===


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{{ABSTRACT_PUBMED_15522303}}
{{ABSTRACT_PUBMED_15522303}}
==Disease==
Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]]


==About this Structure==
==About this Structure==
1O5D is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O5D OCA].  
[[1o5d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O5D OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15522303</ref><references group="xtra"/>
<ref group="xtra">PMID:015522303</ref><references group="xtra"/>
[[Category: Coagulation factor VIIa]]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Young, W B.]]
[[Category: Young, W B.]]
[[Category: Ala190 upa]]
[[Category: Ala190 upa]]
[[Category: Blood clotting]]
[[Category: Conserved water displacement hydrogen bond deficit]]
[[Category: Conserved water displacement hydrogen bond deficit]]
[[Category: Factor viia]]
[[Category: Factor viia]]
[[Category: Hepsin]]
[[Category: Hepsin]]
[[Category: Hydrolase]]
[[Category: S1 site]]
[[Category: S1 site]]
[[Category: Selectivity]]
[[Category: Selectivity]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Trypsin]]
[[Category: Trypsin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:22:40 2009''

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