1h8f: Difference between revisions

Revision as of 19:25, 21 November 2012

Ligands:

Activity:

Non-specific serine/threonine protein kinase, with EC number 2.7.11.1

Structural annotation:
Resources:	CATH : 1H8Fa02, 1H8Fa01, 1H8Fb02, 1H8Fb01 InterPro : Ipr011009, Ipr000719, Ipr008271, Ipr002290 Pfam : PF00069 SCOP : d1h8fa_, d1h8fb_ UniProt : P49841

Functional annotation:
Cellular component:	cytoplasm nucleus beta-catenin destruction complex
Biological process:	positive regulation of protein export from nucleus peptidyl-serine phosphorylation Wnt receptor signaling pathway through beta-catenin ER overload response Wnt receptor signaling pathway negative regulation of apoptosis protein amino acid phosphorylation intracellular signaling cascade glycogen metabolic process
Molecular function:	nucleotide binding ATP binding transferase activity p53 binding NF-kappaB binding kinase activity protein serine/threonine kinase activity protein kinase activity protein binding glycogen synthase kinase 3 activity

Evolutionary conservation:

Toggle Conservation Colors:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

GLYCOGEN SYNTHASE KINASE 3 BETA.GLYCOGEN SYNTHASE KINASE 3 BETA.

Template:ABSTRACT PUBMED 11440715

About this StructureAbout this Structure

1h8f is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Dajani R, Fraser E, Roe SM, Young N, Good V, Dale TC, Pearl LH. Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition. Cell. 2001 Jun 15;105(6):721-32. PMID:11440715

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OCA

[1] Dajani R, Fraser E, Roe SM, Young N, Good V, Dale TC, Pearl LH. Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition. Cell. 2001 Jun 15;105(6):721-32. PMID:11440715

[xtra 1]

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 {{STRUCTURE_1h8f|  PDB=1h8f  |  SCENE=  }}
 ===GLYCOGEN SYNTHASE KINASE 3 BETA.===
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 {{ABSTRACT_PUBMED_11440715}}
 ==About this Structure==
-H8F is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8F OCA].
+[[1h8f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8F OCA].
 ==Reference==
-<ref group="xtra">PMID:11440715</ref><references group="xtra"/>
+<ref group="xtra">PMID:011440715</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Non-specific serine/threonine protein kinase]]
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 [[Category: Insulin pathway]]
 [[Category: Kinase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:27:19 2009''

1h8f: Difference between revisions

Revision as of 19:25, 21 November 2012

GLYCOGEN SYNTHASE KINASE 3 BETA.GLYCOGEN SYNTHASE KINASE 3 BETA.

About this StructureAbout this Structure

ReferenceReference

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